The Role of l Carnitine in Mitochondria, Prevention of Metabolic Inflexibility and Disease Initiation Comprehensive review of the expanding roles of the carnitine pool in metabolic physiology: beyond fatty acid oxidation Journal of Translational Medicine Springer Nature Link Oxidation of Fatty Acids: Ketogenesis Basicmedical Key Short Note On Carnitine Shuttle: Fatty acids are oxidized in mitochondria, and synthesized in the cytoplasm. Long chain fatty acids must form an active intermediate, fatty acyl CoA, before being oxidized inside mitochondria. Catherine L Carnitine is Underrated. New Meta Review Reminds Us Why.