Frontiers Acetaminophen induced liver injury: Molecular mechanism and treatments from natural products Acetaminophen Pathway (toxic doses), Pharmacokinetics Tylenol Avoid or Not to Avoid? Acetaminophen (Tylenol) can deplete glutathione, your body's most important detox antioxidant. This matters even more if your child has an MTHFR gene mutation, which Exposure to acetaminophen and all its metabolites upon 10, 15, and 20 mg kg intravenous acetaminophen in very preterm infants Pediatric Research Sex differences in glutathione metabolism and acetaminophen toxicity